Friday 9 March 2018

LYMPHATIC FILARIASIS



Lymphatic filariasis:-

Causative organism-  wucheria bancrofti


   Lymphatic filariasis is also known as Elephantiasis or filariasis. Infection are transmitted to man by the bite of infective mosquito. Man is a definitive host and mosquito is the intermediate host. Adult worms are usually find in lymphatic system.

Vector- culex mosquito

The mosquito cycle begins when the micro filarae are picked up by the vector mosquito during feedie.
 The following stages of development takes place in the vector-

1.Exsheathing stage:-
The larva comes out of the sheath in which it is enclosed with in 1-2 hours of ingestion. This is known as exsheathing which take place in the stomach of mosquito.

2. First stage larva:-
 The larva is able to penetrate the stomach wall of the mosquito which takes place in 6-12 hours and migrate into the thoraxic muscle, Where it grow and develop into sausage shape. (short and thick)

3. Second stage larva:-
  Larva moults or infective larva (long and thin form). It is highly active and motile. When it is migrate to the mouth of the mosquito it is ready to transmit to the new host. Mosquito is ready to be infective.

Mode of transmission:-
 Filariasis is transmitted by the bite of a infected vector. The parasite is deposited near the site of puncture. It penetrate the skin and reach the lymphatic system.

Incubation period- 8-16 months

Clinical features-
Acute inflammation in lymph glands and vessels.
Filarial fever
lymphangitis
lymphadenitis


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